Prognostic significance of double expressor lymphoma subtype in patient with diffuse large B-cell lymphoma

Background: DLBCL is the most common type of non-Hodgkin lymphoma in Asia and Indonesia. DLBCL, based on cell origin divided into germinal center B-cell-like (GCB) non-GCB subtypes. 20% patients have a molecular profile double expressor (DEL), which has worse prognosis. The study aims to determine relationship between DEL subtypes with clinical stage 3-year overall survival large B-cell (DLBCL) Kariadi General Hospital Semarang.Methods: This sample was 36 from January September 2017. data collection including age diagnosis, location, stage, subtype, subtype survival. Data analysis using chi-square test Kaplan Meier curve.Results: were significantly associated advanced-stage (p: 0.028). had that than GCB non-DEL 0.026 p: 0.006, respectively), rate 38.9% 33.3%. advanced stages also early 0.000), 14.3%.Conclusion: patients, lower thus prognosis